Happy 4th of July!

We started early (as usual) with the fireworks. Those started last weekend. Today is going to be a rough day for Lucas. Even worse since it started thunder and lightning about 8:30a.m. It never starts this early, yet this is the second time this week. I put a Thunder Shirt on him to see if it helps, and I have Benadryl for backup later.


Thankfully I closed the office yesterday. No thanks to my boss. He never called to tell me to close, so I made the unanimous decision to close. :) I'm starting to burn out and need some days off.


In a couple of weeks Lucas goes in for his 6 month cardio workup. I finally made a decision to find a local Cardiologist to take him to. My vet did his first one. They had people come in to do the tests then sent the results out for a Cardiologist to read. The University of Florida did the second one as they did the free DCM screening back in January. I was debating to go back to UF, but an 8 hour road trip really doesn't make sense to have them be his regular Cardiologist. I really did like them though.


Holly was actually called back by the University to continue with the other tests she had done, even though her first came back normal. They had us do a swab test on her first for the PDK4 gene test. These were her results, along with explaining the results:

Results:
DOBERMAN DCM Positive - Heterozygous
COMMENTS Positive Heterozygous (1 copy of the mutated gene and 1 copy of a normal gene) Dogs that are positive heterozygous should be carefully evaluated for signs of disease (Holter monitor and an echocardiogram). If abnormalities are detected, possible treatment options should be discussed
with your veterinarian. Adult dogs that do not show signs of disease and that have other positive
attributes could be bred to mutation negative dogs. Puppies may be screened for the mutation and
over a few generations, mutation negative puppies may be selected to replace the mutation
positive parent and gradually decrease the number of mutation positive dogs in the population.
GENETIC INFO Dilated cardiomyopathy mutation (dcm) is a form of heart disease in the doberman pinscher dog. It is inherited and our laboratory has identified a mutation responsible for the gene in some doberman pinscher. However, it should be noted that in human beings with the same disease,
there are many different genetic mutations which can cause this disease. We do not yet know if
this is the only mutation in the doberman pinscher or if there will be many different mutations.
Please keep in mind that we are continually learning about this disease and recommendations will
be altered as we obtain more information.
Currently our interpretation of the test is:
Negative results:
The absence of the mutation in this dog, does not mean that it will never develop the disease. It
means that it does not have the only known mutation that can cause the disease in the dog at this
time.
Positive results:
Dogs that are positive for the test will not necessarily develop significant heart disease and die
from the disease. Some dogs will develop a very mild form of the disease and will live quite
comfortably, some may need treatment.
Importantly, breeding decisions should be made carefully. At this time we have do not yet know
what percentage of doberman pinscher will be positive for the mutation. However, removal of a
significant number of dogs from the breeding population could be very bad for the doberman
pinscher breed. Remember that dogs that carry this mutation also carry other important good
genes that we do not want to lose from the breed.


Really doesn't make all that much sense to me since even negative result dogs can still develop the disease.


Took them both to work the other day for bring your dog to work day.

Yesterday I had a peeping tom in my bathroom window. This happens once in awhile. I have to laugh while I'm on the potty seeing them. It's a lizard, if you can't tell what it is.

Well I hope everyone has a fantastic 4th! Be safe, and remember, don't drink and drive!